eligibility typically requires a BMI of 35 kg/m or above (or 30 kg/m or above in certain ethnic groups), though thresholds vary by ICB Bariatric surgery referral for eligible patients, typically those with a BMI of 40 kg/m or above, or 35 kg/m or above with significant obesity-related comorbidities, in line with NICE guideline CG189 Structured diabetes prevention programmes for those at risk of type 2 diabetes These pathways offer genuine, monitored, and legally sanctioned routes to improved metabolic health
Circulation 107:363369 Corrado E, Rizzo M, Coppola G, Fattouch K, Novo G, Marturana I, Ferrara F, Novo S (2010) An update on the role of markers of inflammation in atherosclerosis
It acts as a cofactor for essential enzymes involved in tissue repair, antioxidant defense, and even gene expression
Improved sleep quality reported as a positive effect due to melatonin-stimulating properties, but may cause drowsiness if injected in the morning